Influence of CYP3A Metabolizer Status on the Pharmacokinetics and Pharmacodynamics of Amiodarone

The present work was designed to determine whether the individual differences in pharmacokinetics and pharmacodynamics of amiodarone and its N-desethyl metabolite are related to cytochrome CYP3A metabolizer status. Methods: 12 cardiac patients with inducible ventricular tachyarrhythmias during the b...

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Bibliografske podrobnosti

Principais autores:	Stanislav Mičuda, Martin Hodač, Petr Pařízek, Miloslav Pleskot, Luděk Šišpera, Jaroslav Cerman, Jana Maláková, Jiřina Martínková, Vladimír Pidrman
Format:	Artigo
Jezik:	Inglês
Izdano:	Karolinum Press 2000-01-01
Serija:	Acta Medica
Teme:	CYP3A Amiodarone N-desethylamiodarone Cortisol 6β-hydroxycortisol
Online dostop:	https://actamedica.lfhk.cuni.cz/43/3/0095/
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