LC-MS based sphingolipidomic study on A549 human lung adenocarcinoma cell line and its taxol-resistant strain

Abstract Background Resistance to chemotherapy drugs (e.g. taxol) has been a major obstacle in successful cancer treatment. In A549 human lung adenocarcinoma, acquired resistance to the first-line chemotherapy taxol has been a critical problem in clinics. Sphingolipid (SPL) controls various aspects...

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Principais autores:	Hao Huang, Tian-Tian Tong, Lee-Fong Yau, Cheng-Yu Chen, Jia-Ning Mi, Jing-Rong Wang, Zhi-Hong Jiang
格式:	Artigo
语言:	Inglês
出版:	BMC 2018-08-01
丛编:	BMC Cancer
主题:	A549 human lung adenocarcinoma cell line - Taxol-resistant - LC-MS - Sphingolipids - Ceramide
在线阅读:	http://link.springer.com/article/10.1186/s12885-018-4714-x
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