GATA2 haploinsufficient patients lack innate lymphoid cells that arise after hematopoietic cell transplantation

Innate lymphoid cells (ILC) are important barrier tissue immune regulators. They play a pivotal role in early non-specific protection against infiltrating pathogens, regulation of epithelial integrity, suppression of pro-inflammatory immune responses and shaping the intestinal microbiota. GATA2 hapl...

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Detalles Bibliográficos

Principais autores:	Y. F. van Lier, L. Krabbendam, N. J. E. Haverkate, S. S. Zeerleder, C. E. Rutten, B. Blom, H. Spits, M. D. Hazenberg
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2022-10-01
Series:	Frontiers in Immunology
Assuntos:	innate lymphocyte cells (ILCs) NK cells GATA 2 allogeneic haematopoietic cell transplantation reconstitution MonoMAC syndrome
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.1020590/full
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