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The Discovery of Insulin-Regulated Aminopeptidase (IRAP) Inhibitors: A Literature Review

Insulin-Regulated Aminopeptidase (IRAP, EC 3.4.11.3) is a multi-tasking member of the M1 family of zinc aminopeptidases. Among its diverse biological functions, IRAP is a regulator of oxytocin levels during late stages of pregnancy, it affects cellular glucose uptake by trafficking of the glucose tr...

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Autors principals: Dimitris Georgiadis, Angeliki Ziotopoulou, Eleni Kaloumenou, Angelos Lelis, Antonia Papasava
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020-09-01
Col·lecció:Frontiers in Pharmacology
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Accés en línia:https://www.frontiersin.org/article/10.3389/fphar.2020.585838/full
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