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The Identification and Validation of Two Heterogenous Subtypes and a Risk Signature Based on Ferroptosis in Hepatocellular Carcinoma

BackgroundFerroptosis is essential for tumorigenesis and progression of hepatocellular carcinoma (HCC). The heterogeneity of ferroptosis and its relationship with tumor microenvironment (TME) have still remain elusive.MethodsBased on 74 ferroptosis related genes (FRGs) and 3,933 HCC samples from 32...

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Uloženo v:
Hlavní autoři: Zaoqu Liu, Libo Wang, Long Liu, Taoyuan Lu, Dechao Jiao, Yuling Sun, Xinwei Han
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021-03-01
Edice:Frontiers in Oncology
Témata:
ferroptosis
hepatocellular carcinoma
tumor microenvironment
molecular subtype
immunotherapy
On-line přístup:https://www.frontiersin.org/articles/10.3389/fonc.2021.619242/full
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