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The role of genetically predicted serum iron levels on neurodegenerative and cardiovascular traits

Abstract Iron is an essential mineral that supports numerous biological functions. Studies have reported associations between iron dysregulation and certain cardiovascular and neurodegenerative diseases, but the direction of influence is not clear. Our goal was to use computational approaches to bet...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Wiame Belbellaj, Frida Lona-Durazo, Cinzia Bodano, David Busseuil, Marie-Christyne Cyr, Edoardo Fiorillo, Antonella Mulas, Sylvie Provost, Maristella Steri, Toshiko Tanaka, Brett Vanderwerff, Jiongming Wang, Ross P. Byrne, Francesco Cucca, Marie-Pierre Dubé, Luigi Ferrucci, Russell L. McLaughlin, Jean-Claude Tardif, Matthew Zawistowski, Sarah A. Gagliano Taliun
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Portfolio 2024-10-01
Rangatū:Scientific Reports
Ngā marau:
Serum iron
Genetic correlation
Mendelian randomization (MR)
Sex-stratified
Cardiovascular
Neurodegeneration
Urunga tuihono:https://doi.org/10.1038/s41598-024-76245-9
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