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The effects of nitric oxide on the immune system during Trypanosoma cruzi infection

Trypanosoma cruzi infection triggers substantial production of nitric oxide (NO), which has been shown to have protective and toxic effects on the host's immune system. Sensing of trypomastigotes by phagocytes activates the inducible NO-synthase (NOS2) pathway, which produces NO and is largely respo...

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Autori principali: Fredy RS Gutierrez, Tiago WP Mineo, Wander R Pavanelli, Paulo MM Guedes, João S Silva
Natura: Artigo
Lingua:Inglês
Pubblicazione: Fundação Oswaldo Cruz (FIOCRUZ) 2009-07-01
Serie:Memorias do Instituto Oswaldo Cruz
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Accesso online:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000900030
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