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Clonal hematopoiesis is associated with reduced response to atezolizumab in non-small cell lung cancer

Background The acquisition of somatic mutations associated with the expansion of certain hematopoietic stem cells is known as clonal hematopoiesis (CH). Despite evidence of CH association with age-related pro-inflammatory diseases, little is known about its role in the response to antitumor immune m...

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Huvudupphov: Ira Mellman, Minu Srivastava, Mark I McCarthy, Kipper Fletez-Brant, Christian Hammer, Barzin Nabet, Vylyny Chat
Materialtyp: Artigo
Språk:Inglês
Utgiven: BMJ Publishing Group 2025-09-01
Serie:Journal for ImmunoTherapy of Cancer
Länkar:https://jitc.bmj.com/content/13/9/e011565.full
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