Fibroblast growth factor 21 attenuates iron overload-induced liver injury and fibrosis by inhibiting ferroptosis

Ferroptosis plays a role in several diseases such as iron overload-induced liver diseases. Manipulation of ferroptosis has been explored as a potential therapeutic strategy to treat related diseases. Numerous antioxidants have been identified to control ferroptosis but the cell-autonomous mechanisms...

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Detalhes bibliográficos

Principais autores:	Aimin Wu, Bin Feng, Jie Yu, Lijun Yan, Lianqiang Che, Yong Zhuo, Yuheng Luo, Bing Yu, De Wu, Daiwen Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2021-10-01
coleção:	Redox Biology
Assuntos:	Fibroblast growth factor 21 (FGF21) Ferroptosis Oxidative stress Lipid peroxidation Ubiquitination
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2213231721002901
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