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Homeoprotein Msx1-PIASy Interaction Inhibits Angiogenesis

Previously, we demonstrated that the homeoprotein Msx1 interaction with p53 inhibited tumor growth by inducing apoptosis. However, Msx1 can exert its tumor suppressive effect through the inhibition of angiogenesis since growth of the tumor relies on sufficient blood supply from the existing vessels...

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Principais autores: Myung Jin Son, Seung Bae Rho, Kwangbae Kim, Mijung Oh, Chaeyeon Son, Sang Yong Song, Kyoungsook Park
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2020-08-01
Serier:Cells
Fag:
Msx1
PIASy
VEGF
angiogenesis
protein stabilization
Online adgang:https://www.mdpi.com/2073-4409/9/8/1854
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