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Exploration into the MLL4/WRAD Enzyme-Substrate Network: Systematic In Vitro Identification of CFP1 as a Potential Non-Histone Substrate of the MLL4 Lysine Methyltransferase

Lysine methylation is a critical post-translational modification catalyzed by lysine methyltransferases (KMTs), originally characterized in the regulation of histones. However, the breadth of non-histone targets remains largely unexplored. Here, we used a systematic peptide array-based approach to d...

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Autors principals: Mullen Boulter, Ryan Collins, Kyle K. Biggar
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2025-10-01
Col·lecció:Epigenomes
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Accés en línia:https://www.mdpi.com/2075-4655/9/4/41
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