Structural basis of the phosphoramidate <i>N</i>-benzimidazole group’s influence on modified primer extension efficiency by Taq DNA polymerase

We recently proposed a novel class of nucleic acid derivatives – phosphoramidate benzoazole oligonucleotides (PABAOs). In these compounds, one of the non­bridging oxygen atoms is replaced by a phosphoramidate N-­ben­zoazole group, such as benzimidazole, dimethylbenzimidazole, benzoxazole, or benzoth...

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Bibliografski detalji

Glavni autori:	A. A. Berdugin, V. M. Golyshev, A. A. Lomzov
Format:	Artigo
Jezik:	Inglês
Izdano:	Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders 2025-12-01
Serija:	Вавиловский журнал генетики и селекции
Teme:	<i>n</i> -­бензимидазольные олигонуклеотиды фао молекулярная динамика структура taq днк­ полимераза молекулярная диагностика
Online pristup:	https://vavilov.elpub.ru/jour/article/view/4890
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