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The SNP rs6859 in NECTIN2 gene is associated with underlying heterogeneous trajectories of cognitive changes in older adults

Abstract Background Functional decline associated with dementia, including in Alzheimer’s disease (AD), is not uniform across individuals, and respective heterogeneity is not yet fully explained. Such heterogeneity may in part be related to genetic variability among individuals. In this study, we in...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Aravind Lathika Rajendrakumar, Konstantin G. Arbeev, Olivia Bagley, Anatoliy I. Yashin, Svetlana Ukraintseva, for the Alzheimer’s Disease Neuroimaging Initiative
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2024-02-01
Rangatū:BMC Neurology
Ngā marau:
MMSE
NECTIN2
rs6859
Heterogeneity
Trajectory analysis
Latent class
Urunga tuihono:https://doi.org/10.1186/s12883-024-03577-4
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