Search of reference biomarkers reflecting orbital tissue remodeling in the course of Graves’ orbitopathy

INTRODUCTION: Graves’ orbitopathy (GO) is a complication in Graves’ disease (GD) that causes disfigurement and sometimes blindness. The pathogenesis of GO remains unknown, while its symptoms demonstrate dependence between the thyroid gland and the orbit. The ongoing inflammatory process in retrobulb...

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Main Authors: Przemyslaw Pawlowski, Izabela Poplawska, Janusz Mysliwiec, Willem A. Dik, Anja Eckstein, Utta Berchner-Pfannschmidt, Robert Milewski, Slawomir Lawicki, Zofia Dzieciol-Anikiej, Robert Rejdak, Joanna Reszec
Format: Artigo
Jezik:Inglês
Izdano: Via Medica 2020-04-01
Serija:Folia Histochemica et Cytobiologica
Teme:
Graves’ orbitopathy
CD34
IGF-1R
PPAR-g
CD68
TGF-b
FGF-b
Foxp-3
tissue remodeling
autoimmunity
IHC
Online dostop:https://journals.viamedica.pl/folia_histochemica_cytobiologica/article/view/60911
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