Suppression of inflammation-induced lung cancer cells proliferation and metastasis by exiguaflavanone A and exiguaflavanone B from Sophora exigua root extract through NLRP3 inflammasome pathway inhibition

Objective: Non-small cell lung cancer (NSCLC) is recognized for its aggressive nature and propensity for high rates of metastasis. The NLRP3 inflammasome pathway plays a vital role in the progression of NSCLC. This study aimed to investigate the effects of S. exigua extract and its active compounds...

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Hlavní autoři:	Punnida Arjsri, Kamonwan Srisawad, Warathit Semmarath, Sonthaya Umsumarng, Lapamas Rueankham, Aroonchai Saiai, Methee Rungrojsakul, Trinnakorn Katekunlaphan, Songyot Anuchapreeda, Pornngarm Dejkriengkraikul
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-11-01
Edice:	Frontiers in Pharmacology
Témata:	Sophora exigua exiguaflavanone non-small cell lung cancer cancer progression and metastasis NLRP3 inflammasome pathway
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1243727/full
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