Synthetic RNA Silencing of Actinorhodin Biosynthesis in Streptomyces coelicolor A3(2).

We demonstrate the first application of synthetic RNA gene silencers in Streptomyces coelicolor A3(2). Peptide nucleic acid and expressed antisense RNA silencers successfully inhibited actinorhodin production. Synthetic RNA silencing was target-specific and is a new tool for gene regulation and meta...

Descripció completa

Dades bibliogràfiques

Autors principals:	Gabriel C Uguru, Madhav Mondhe, Shan Goh, Andrew Hesketh, Mervyn J Bibb, Liam Good, James E M Stach
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2013-01-01
Col·lecció:	PLoS ONE
Accés en línia:	https://doi.org/10.1371/journal.pone.0067509
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!