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Identifying a Hypoxia-Related Long Non-Coding RNAs Signature to Improve the Prediction of Prognosis and Immunotherapy Response in Hepatocellular Carcinoma

Abstract Background: Both hypoxia and long non-coding RNAs (lncRNAs) contribute to the tumor progression in hepatocellular carcinoma (HCC). We sought to establish a hypoxia-related lncRNA signature and explore its correlation with immunotherapy response in HCC.Materials and Methods: Hypoxia-related...

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Principais autores: Pingfei Tang, Weiming Qu, Taoli Wang, Minji Liu, Dajun Wu, Lin Tan, Hongbing Zhou
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-11-01
Serier:Frontiers in Genetics
Fag:
hypoxia
lncRNA (long non-coding RNA)
hepatocellular carcinoma
prognostic signature
tumor immune microenvironment
immunotherapy response
Online adgang:https://www.frontiersin.org/articles/10.3389/fgene.2021.785185/full
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