A New and Efficient Synthesis of 6-O-Methylscutellarein, the Major Metabolite of the Natural Medicine Scutellarin

In this paper, a new and efficient synthesis of 6-O-methylscutellarein (3), the major metabolite of the natural medicine scutellarin, is reported. Two hydroxyl groups at C-4′ and C-7 in 2 were selectively protected by chloromethyl methyl ether after the reaction conditions were optimized, then 6-O-m...

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Detalhes bibliográficos

Principais autores:	Wei Zhang, Ze-Xi Dong, Ting Gu, Nian-Guang Li, Peng-Xuan Zhang, Wen-Yu Wu, Shao-Peng Yu, Yu-Ping Tang, Jian-Ping Yang, Zhi-Hao Shi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2015-06-01
coleção:	Molecules
Assuntos:	scutellarin scutellarein 6-O-methylscutellarein metabolite synthesis
Acesso em linha:	http://www.mdpi.com/1420-3049/20/6/10184
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