Lactic Acid Fermentation Is Required for NLRP3 Inflammasome Activation

Activation of the Nod-like receptor 3 (NLRP3) inflammasome is important for activation of innate immune responses, but improper and excessive activation can cause inflammatory disease. We previously showed that glycolysis, a metabolic pathway that converts glucose into pyruvate, is essential for NLR...

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Κύριοι συγγραφείς:	Hsin-Chung Lin, Yu-Jen Chen, Yau-Huei Wei, Hsin-An Lin, Chien-Chou Chen, Tze-Fan Liu, Yi-Lin Hsieh, Kuo-Yang Huang, Kuan-Hung Lin, Hsueh-Hsiao Wang, Lih-Chyang Chen
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Frontiers Media S.A. 2021-03-01
Σειρά:	Frontiers in Immunology
Θέματα:	glycolysis lactic acid fermentation pyruvate oxidation NLRP3 inflammasome inflammation
Διαθέσιμο Online:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.630380/full
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