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Follicular helper-T cells restore CD8+-dependent antitumor immunity and anti-PD-L1/PD-1 efficacy

Background T follicular helper cells (Tfh) are essential to shape B cell response during germinal center formation. Tfh accumulation has been reported in various human cancers, with positive or negative prognostic roles. However, the mechanisms explaining the accumulation of Tfh and their role in ca...

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Detalles Bibliográficos
Principais autores: Francois Ghiringhelli, Valentin Derangere, Marion Thibaudin, Caroline Truntzer, Bertrand Routy, Fanny Chalmin, Cédric Rébé, Julie Niogret, Hélène Berger, Romain Mary, Elise Ballot, Christophe Hibos, Léa Hampe, David Rageot, Théo Accogli, Philippe Joubert, James Harker, Frederique Vegran
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Publishing Group 2021-06-01
Series:Journal for ImmunoTherapy of Cancer
Acceso en liña:https://jitc.bmj.com/content/9/6/e002157.full
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