The MYC/TXNIP axis mediates NCL-Suppressed CD8+T cell immune response in lung adenocarcinoma

Abstract Background Lung adenocarcinoma is a deadly malignancy with immune evasion playing a key role in tumor progression. Glucose metabolism is crucial for T cell function, and the nucleolar protein NCL may influence T cell glucose metabolism. This study aims to investigate NCL’s role in T cell gl...

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Hlavní autoři:	Dan Xiao, Tanxiu Chen, Xinlin Yu, Ying Song, Yigang Liu, Wei Yan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-05-01
Edice:	Molecular Medicine
Témata:	Lung adenocarcinoma CD8+ T cells Glucose metabolism Immune escape NCL MYC
On-line přístup:	https://doi.org/10.1186/s10020-025-01224-3
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