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Cell-penetrating peptides enhance the transduction of adeno-associated virus serotype 9 in the central nervous system

Recombinant adeno-associated viruses (rAAVs) have been widely used in the gene therapy field for decades. However, because of the challenge of effectively delivering rAAV vectors through the blood-brain barrier (BBB), their applications for treatment of central nervous system (CNS) diseases are quit...

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Autors principals: Yuan Meng, Dong Sun, Yiyan Qin, Xiaoyi Dong, Guangzuo Luo, Ying Liu
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021-06-01
Col·lecció:Molecular Therapy: Methods & Clinical Development
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S2329050121000346
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