Silk Fibroin Nanoparticles for Enhanced Cuproptosis and Immunotherapy in Pancreatic Cancer Treatment

Abstract Cuproptosis is a newly discovered copper ion‐dependent programmed cell death. Elesclomol (ES) is a Cu2+ transporter that delivers Cu2+ into tumor cells, causing cell death at toxic doses. However, ES has a short blood half‐life, limiting its accumulation in tumors. This study introduces Tus...

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Principais autores:	Si Gao, Haodong Ge, Lili Gao, Ying Gao, Shuibin Tang, Yiming Li, Zhiqing Yuan, Wei Chen
Format:	Artigo
Jezik:	Inglês
Izdano:	Wiley 2025-05-01
Serija:	Advanced Science
Teme:	cancer therapy cuproptosis elesclomol silk fibroin αPDL‐1
Online dostop:	https://doi.org/10.1002/advs.202417676
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