Cryo-EM Structures of Two Bacteriophage Portal Proteins Provide Insights for Antimicrobial Phage Engineering

Widespread antibiotic resistance has returned attention to bacteriophages as a means of managing bacterial pathogenesis. Synthetic biology approaches to engineer phages have demonstrated genomic editing to broaden natural host ranges, or to optimise microbicidal action. Gram positive pathogens cause...

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Главные авторы:	Abid Javed, Hugo Villanueva, Shadikejiang Shataer, Sara Vasciaveo, Renos Savva, Elena V. Orlova
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2021-12-01
Серии:	Viruses
Предметы:	bacteriophage GA1 phiCPV4 portal protein cryo electron microscopy structural analysis
Online-ссылка:	https://www.mdpi.com/1999-4915/13/12/2532
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