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The Effect of C-Reactive Protein Isoforms on Nitric Oxide Production by U937 Monocytes/Macrophages

Inflammation is regulated by many endogenous factors including estrogen, a steroid hormone that declines with increasing age, leading to excessive inflammation in the elderly. C-reactive protein (CRP) is an acute phase inflammatory protein that exists in two forms, native CRP (nCRP) and monomeric CR...

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Principais autores: Nicola R. Sproston, Mohamed El Mohtadi, Mark Slevin, William Gilmore, Jason J. Ashworth
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018-07-01
Serier:Frontiers in Immunology
Fag:
C-reactive protein
nitric oxide
inflammation
native C-reactive protein
monomeric C-reactive protein
estrogen
Online adgang:https://www.frontiersin.org/article/10.3389/fimmu.2018.01500/full
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