Metabolic enzyme clustering by coiled coils improves the biosynthesis of resveratrol and mevalonate

Abstract The clustering of biosynthetic enzymes is used in nature to channel reaction products and increase the yield of compounds produced by multiple reaction steps. The coupling of multiple enzymes has been shown to increase the biosynthetic product yield. Different clustering strategies have par...

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Auteurs principaux:	Tina Fink, Bojana Stevović, René Verwaal, Johannes A. Roubos, Rok Gaber, Mojca Benčina, Roman Jerala, Helena Gradišar
Format:	Artigo
Langue:	Inglês
Publié:	SpringerOpen 2020-05-01
Collection:	AMB Express
Sujets:	Designed coiled-coil dimers Enzyme clustering Biosynthesis Resveratrol Mevalonate
Accès en ligne:	http://link.springer.com/article/10.1186/s13568-020-01031-5
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