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The size of the EB cap determines instantaneous microtubule stability

The function of microtubules relies on their ability to switch between phases of growth and shrinkage. A nucleotide-dependent stabilising cap at microtubule ends is thought to be lost before this switch can occur; however, the nature and size of this protective cap are unknown. Using a microfluidics...

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Principais autores: Christian Duellberg, Nicholas I Cade, David Holmes, Thomas Surrey
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2016-04-01
Serier:eLife
Fag:
TIRF microscopy
EB proteins
microtubule dynamic instability
end tracking
in vitro reconstitution
microfluids
Online adgang:https://elifesciences.org/articles/13470
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