HSP70 positively regulates translation by interacting with the IRES and stabilizes the viral structural proteins VP1 and VP3 to facilitate duck hepatitis A virus type 1 replication

Abstract The maintenance of viral protein homeostasis depends on the interaction between host cell proteins and viral proteins. As a molecular chaperone, heat shock protein 70 (HSP70) has been shown to play an important role in viral infection. Our results showed that HSP70 can affect translation, r...

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Detalhes bibliográficos

Principais autores:	Yurui Jiang, Chenxia Xu, Anchun Cheng, Mingshu Wang, Wei Zhang, Xinxin Zhao, Qiao Yang, Ying Wu, Shaqiu Zhang, Bin Tian, Juan Huang, Xumin Ou, Di Sun, Yu He, Zhen Wu, Dekang Zhu, Renyong Jia, Shun Chen, Mafeng Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-05-01
coleção:	Veterinary Research
Assuntos:	DHAV-1 HSP70 IRES VP1 VP3 translation
Acesso em linha:	https://doi.org/10.1186/s13567-024-01315-9
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