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Entry of Challenge Virus Standard (CVS) -11 into N2a cells via a clathrin-mediated, cholesterol-, dynamin-, pH-dependent endocytic pathway

Abstract Background Rabies virus (RABV), a member of Lyssavirus of Rhabdoviridae family, is a kind of negative-strand RNA virus. The zoonosis caused by RABV leads to high mortality in animals and humans. Though with the extensive investigation, the mechanisms of RABV entry into cells have not been w...

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Main Authors: Jie Gao, Xinyu Wang, Mingxin Zhao, Enhua Liu, Ming Duan, Zhenhong Guan, Yidi Guo, Maolin Zhang
Format: Artigo
Language:Inglês
Published: BMC 2019-06-01
Series:Virology Journal
Subjects:
RABV
N2a
Clathrin
Caveolin-1
Endocytosis
Online Access:http://link.springer.com/article/10.1186/s12985-019-1186-9
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