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Downregulation of Drp1 and Fis1 Inhibits Mitochondrial Fission and Prevents High Glucose-Induced Apoptosis in Retinal Endothelial Cells

Diabetic retinopathy is a prevalent microvascular complication characterized by apoptotic vascular cell loss in the retina. Previous studies have shown that high glucose (HG)-induced mitochondrial fragmentation plays a critical role in promoting retinal vascular cell apoptosis. Here, we investigated...

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Autors principals: Dongjoon Kim, Aravind Sankaramoorthy, Sayon Roy
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2020-07-01
Col·lecció:Cells
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Accés en línia:https://www.mdpi.com/2073-4409/9/7/1662
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