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A Zinc-Dependent Metalloproteinase of Brucella abortus Is Required in the Intracellular Adaptation of Macrophages

Brucella abortus is a pathogen that survives in macrophages. Several virulence factors participate in this process, including the open reading frame (ORF) BAB1_0270 codifying for a zinc-dependent metalloproteinase (ZnMP). Here, its contribution in the intracellular adaptation of B. abortus was analy...

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Principais autores: Leonardo A. Gómez, Francisco I. Alvarez, Raúl E. Molina, Rodrigo Soto-Shara, Carla Daza-Castro, Manuel R. Flores, Yrvin León, Angel A. Oñate
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020-07-01
Serier:Frontiers in Microbiology
Fag:
host-pathogen interaction
virulence
attenuation
toxin-anti-toxin systems
gene regulation
Online adgang:https://www.frontiersin.org/article/10.3389/fmicb.2020.01586/full
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