Safety and efficacy of low-dose intravenous arsenic trioxide in systemic lupus erythematosus: an open-label phase IIa trial (Lupsenic)

Abstract Background Lupus animal model has shown that arsenic trioxide (ATO), a treatment of acute promyelocytic leukaemia, could be effective in SLE. This is the first clinical study to determine the safety and efficacy of a short course of intravenous ATO in patients with active SLE. Methods This...

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Hlavní autoři:	Mohamed Hamidou, Antoine Néel, Joel Poupon, Zahir Amoura, Mikael Ebbo, Jean Sibilia, Jean-Francois Viallard, Benjamin Gaborit, Christelle Volteau, Jean Benoit Hardouin, Eric Hachulla, François Rieger
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2021-03-01
Edice:	Arthritis Research & Therapy
Témata:	Systemic lupus erythematosus Autoimmune diseases Treatment Arsenic trioxide Phase II clinical trial
On-line přístup:	https://doi.org/10.1186/s13075-021-02454-6
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