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Age, but Not Amyloidosis, Induced Changes in Global Levels of Histone Modifications in Susceptible and Disease-Resistant Neurons in Alzheimer’s Disease Model Mice

There is increasing interest in the role of epigenetic alterations in Alzheimer’s disease (AD). The epigenome of every cell type is distinct, yet data regarding epigenetic change in specific cell types in aging and AD is limited. We investigated histone tail modifications in neuronal subtypes in wil...

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Бібліографічні деталі
Автори: Marcus Dyer, Andrew J. Phipps, Stanislaw Mitew, Phillippa C. Taberlay, Adele Woodhouse
Формат: Artigo
Мова:Inglês
Опубліковано: Frontiers Media S.A. 2019-04-01
Серія:Frontiers in Aging Neuroscience
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Онлайн доступ:https://www.frontiersin.org/article/10.3389/fnagi.2019.00068/full
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