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Association of BACE1 Gene Polymorphism with Cerebellar Volume but Not Cognitive Function in Normal Individuals

Aims: β-Site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1) is a biological and positional candidate gene for Alzheimer’s disease (AD). Previous studies found that BACE1-null mice had impaired performance on cognition and neurodegeneration during the aging process. Additionally, a synonym...

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Uloženo v:
Hlavní autoři: Alex Tsai, Chu-Chung Huang, Albert C. Yang, Mu-En Liu, Pei-Chi Tu, Chen-Jee Hong, Ying-Jay Liou, Jin-Fan Chen, Ching-Po Lin, Shih-Jen Tsai
Médium: Artigo
Jazyk:Inglês
Vydáno: Karger Publishers 2012-12-01
Edice:Dementia and Geriatric Cognitive Disorders Extra
Témata:
β-Site amyloid precursor protein-cleaving enzyme 1
Volumetry
Cognition
Polymorphism
Cerebellum
On-line přístup:http://www.karger.com/Article/FullText/345980
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