Tet methylcytosine dioxygenase 2(TET2)-dependent epigenetic regulation in the pathogenesis of polycystic ovary syndrome

Abstract Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder and a major cause of female infertility. While epigenetic dysregulation, notably DNA methylation, has been recognized as a key driver of PCOS pathogenesis, the specific involvement of active demethylation mediated by Ten-Eleve...

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Auteurs principaux:	Kailu Liu, Yanli Hong, Qian Gao, Jingyu Huang, Li Liu, Yueyi Li, Yunteng Liang, Shuxuan Zhang, Xi He, Xiaowei Nie
Format:	Artigo
Langue:	Inglês
Publié:	Springer 2026-03-01
Collection:	Cellular and Molecular Life Sciences
Sujets:	PCOS Epigenetic modifications 5-hydroxymethylcytosine modification TET2 Autophagy
Accès en ligne:	https://doi.org/10.1007/s00018-026-06134-z
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