A receptor-antibody hybrid hampering MET-driven metastatic spread
Abstract Background The receptor encoded by the MET oncogene and its ligand Hepatocyte Growth Factor (HGF) are at the core of the invasive-metastatic behavior. In a number of instances genetic alterations result in ligand-independent onset of malignancy (MET addiction). More frequently, ligand stimu...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2021-01-01
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| coleção: | Journal of Experimental & Clinical Cancer Research |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s13046-020-01822-5 |
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