The Expression and Prognostic Impact of Immune Cytolytic Activity-Related Markers in Human Malignancies: A Comprehensive Meta-analysis

BackgroundRecently, immune-checkpoint blockade has shown striking clinical results in different cancer patients. However, a significant inter-individual and inter-tumor variability exists among different cancers. The expression of the toxins granzyme A (GZMA) and perforin 1 (PRF1), secreted by effec...

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Podrobná bibliografie

Hlavní autoři:	Constantinos Roufas, Dimitrios Chasiotis, Anestis Makris, Christodoulos Efstathiades, Christos Dimopoulos, Apostolos Zaravinos
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2018-02-01
Edice:	Frontiers in Oncology
Témata:	granzyme A perforin 1 immune cytolytic activity metastasis cancer immunotherapy survival rate
On-line přístup:	http://journal.frontiersin.org/article/10.3389/fonc.2018.00027/full
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