Deciphering the tumor-suppressive role of RBMS3 in lung adenocarcinoma through genomic insights into prognosis and mechanisms

Abstract Lung adenocarcinoma (LUAD) is a leading cause of cancer-related mortality, underscoring the urgent need for novel biomarkers and therapeutic targets. Through transcriptomic analysis of 4456 genes in TCGA-LUAD cohorts, we identified RBMS3 as a significantly downregulated tumor suppressor (lo...

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Detalhes bibliográficos

Principais autores:	Li Lv, Tengxiang Zhong, Zhenkun Li, Wenhui Zhang, Yi Zhang, Ying Liang, Rongqing Li, Mingxia Ding, Jie Lin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-03-01
coleção:	Scientific Reports
Assuntos:	Lung adenocarcinoma RBMS3 Prognosis Differentially expressed genes Risk score model
Acesso em linha:	https://doi.org/10.1038/s41598-025-95432-w
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