Analysis of a cAMP regulated coactivator family reveals an alternative phosphorylation motif for AMPK family members.
The second messenger cAMP stimulates cellular gene expression via the PKA-mediated phosphorylation of the transcription factor CREB and through dephosphorylation of the cAMP-responsive transcriptional coactivators (CRTCs). Under basal conditions, CRTCs are phosphorylated by members of the AMPK famil...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science (PLoS)
2017-01-01
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| Col·lecció: | PLoS ONE |
| Accés en línia: | http://europepmc.org/articles/PMC5325614?pdf=render |
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