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Novel Isocratic HPLC Method for Simultaneous Estimation of Sacubitril and Valsartan in Bulk and Formulation

Abstract In compliance with ICH requirements, a new selective, precise, and accurate reverse-phase High-Performance Liquid Chromatographic method for valsartan and sacubitril quantification was developed and validated. Eluents were detected at 284 nm. The HPLC method was designed utilizing a C18, (1...

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Autori principali: Harshavardhan Rajendra Karnik, Ambar Bhikasaheb Marne, Ashwin Bhanudas Kuchekar, Ashwini Ramkrishna Gawade
Natura: Artigo
Lingua:Inglês
Pubblicazione: Instituto de Tecnologia do Paraná (Tecpar) 2025-11-01
Serie:Brazilian Archives of Biology and Technology
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Accesso online:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132025000100618&lng=en&tlng=en
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