Novel chikungunya vaccine candidate with an IRES-based attenuation and host range alteration mechanism.

Chikungunya virus (CHIKV) is a reemerging mosquito-borne pathogen that has recently caused devastating urban epidemics of severe and sometimes chronic arthralgia. As with most other mosquito-borne viral diseases, control relies on reducing mosquito populations and their contact with people, which ha...

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Autors principals:	Kenneth Plante, Eryu Wang, Charalambos D Partidos, James Weger, Rodion Gorchakov, Konstantin Tsetsarkin, Erin M Borland, Ann M Powers, Robert Seymour, Dan T Stinchcomb, Jorge E Osorio, Ilya Frolov, Scott C Weaver
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2011-07-01
Col·lecció:	PLoS Pathogens
Accés en línia:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21829348/pdf/?tool=EBI
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