Microglial Hemoxygenase-1 Deletion Reduces Inflammation in the Retina of Old Mice with Tauopathy

Tauopathies such as Alzheimer’s disease are characterized by the accumulation of neurotoxic aggregates of tau protein. With aging and, especially, in Alzheimer’s patients, the inducible enzyme heme oxygenase 1 (HO-1) progressively increases in microglia, causing iron accumulation, neuroinflammation,...

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Bibliografiske detaljer

Principais autores:	José A. Fernández-Albarral, Elena Salobrar-García, José A. Matamoros, Cristina Fernández-Mendívil, Eric del Sastre, Lejing Chen, Rosa de Hoz, Inés López-Cuenca, Lidia Sánchez-Puebla, José M. Ramírez, Juan J. Salazar, Manuela G. Lopez, Ana I. Ramírez
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2022-10-01
Serier:	Antioxidants
Fag:	tauopathies heme oxygenase 1 (HO-1) retina microglia macroglia neuroinflammation
Online adgang:	https://www.mdpi.com/2076-3921/11/11/2151
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