MRS suggests multi-regional inflammation and white matter axonal damage at 11 years following perinatal HIV infection

The neurological changes in children living with perinatal HIV (PHIV) on antiretroviral therapy (ART) can be studied at a metabolic level through proton magnetic resonance spectroscopy. While previous studies in children have largely focused on individual metabolite changes, investigating patterns w...

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Autori principali:	Amy S. Graham, Martha J. Holmes, Francesca Little, Els Dobbels, Mark F. Cotton, Barbara Laughton, Andre van der Kouwe, Ernesta M. Meintjes, Frances C. Robertson
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2020-01-01
Serie:	NeuroImage: Clinical
Soggetti:	Antiretroviral therapy Basal ganglia HIV Midfrontal gray matter Peritrigonal white matter Proton magnetic resonance spectroscopy
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2213158220303429
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