The impact of dysfunctional variants of ABCG2 on hyperuricemia and gout in pediatric-onset patients
Abstract Background ABCG2 is a high-capacity urate transporter that plays a crucial role in renal urate overload and extra-renal urate underexcretion. Previous studies have suggested an association between hyperuricemia and gout susceptibility relative to dysfunctional ABCG2 variants, with rs2231142...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2019-03-01
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| coleção: | Arthritis Research & Therapy |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s13075-019-1860-8 |
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