Pharmacokinetic Drug Interaction Study of Sorafenib and Morphine in Rats
A combination of the tyrosine kinase inhibitor—sorafenib—and the opioid analgesic—morphine—can be found in the treatment of cancer patients. Since both are substrates of P-glycoprotein (P-gp), and sorafenib is also an inhibitor of P-gp, their co-administration may affect their pharmacokinetics, and...
Bewaard in:
| Hoofdauteurs: | , , , , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
MDPI AG
2021-12-01
|
| Reeks: | Pharmaceutics |
| Onderwerpen: | |
| Online toegang: | https://www.mdpi.com/1999-4923/13/12/2172 |
| Tags: |
Geen labels, Wees de eerste die dit record labelt!
|