Genomic Breakpoints’ Characterization of a Large <i>CHEK2</i> Duplication in an Italian Family with Hereditary Breast Cancer
<i>CHEK2</i> (checkpoint kinase 2; MIM# 604373) is a tumor suppressor gene that encodes a serine threonine kinase involved in pathways such as DNA repair, cell cycle arrest, mitosis, and apoptosis. Pathogenic variants in <i>CHEK2</i> contribute to a moderately increased risk of breast and other canc...
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| Автори: | , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
MDPI AG
2022-06-01
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| Серія: | Diagnostics |
| Предмети: | |
| Онлайн доступ: | https://www.mdpi.com/2075-4418/12/7/1520 |
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