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The emergence and biological characteristics of linezolid-resistant Clostridioides difficile isolates in the Asia-Pacific region

Linezolid-resistant Clostridioides difficile, conferred by the acquisition of cfr-like genes, has been reported in Europe and America. However, the emergence of linezolid resistance in C. difficile in the Asia-Pacific region and its impacts on C. difficile pathogenicity remain unclear. In this study...

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Main Authors: Yu Chen, Xinwei Chen, Hangcong Xu, Heng Shen, Xing Liu, Fen Wan, Yuning Han, Xiaojun Song, Jun Li, Hong Du, Xingli Fan, Yan Wu, Yun Luo, Dazhi Jin
Format: Artigo
Language:Inglês
Published: Taylor & Francis Group 2026-12-01
Series:Emerging Microbes and Infections
Subjects:
Clostridioides difficile
linezolid resistance
cfr-like genes
CRISPRi
pathogenicity
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2026.2627070
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