Dengue virus 4/2 envelope domain chimeric virus panel maps type-specific responses against dengue serotype 2

ABSTRACT The DENV envelope (E) and pre-membrane (prM) glycoproteins are primary targets of serologic immunity after infection and vaccination. Of these, serotype-specific (TS) antibodies typically target E domains, while serotype cross-reactive (CR) antibodies typically the target prM protein and co...

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Principais autores:	Deanna R. Zhu, Alecia J. Rajesh, Rita M. Meganck, Ellen F. Young, Jennifer E. Munt, Victor L. Tse, Boyd Yount, Helen Conrad, Laura White, Sandra Henein, Aravinda M. DeSilva, Ralph S. Baric
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology 2023-10-01
Series:	mBio
Assuntos:	dengue neutralizing antibodies reverse genetics
Acceso en liña:	https://journals.asm.org/doi/10.1128/mbio.00818-23
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