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HIV proviral transcription and infectivity are enhanced by neddylation

ABSTRACT A spreading infection can quickly restart from the persistent reservoir of cells harboring HIV proviruses if antiretroviral therapy (ART) is stopped. HIV transcription can also be increased by latency-reversing agents (LRAs) during ART. Neddylation is a post-translational modification that...

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Autors principals: Cristina C. Vaca, Hannah Hudson, Isabelle Clerc, Chisu Song, Richard T. D'Aquila
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2025-10-01
Col·lecció:Journal of Virology
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Accés en línia:https://journals.asm.org/doi/10.1128/jvi.00968-25
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