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Effect of HIF-1α expression inhibition by RNA interference on radiosensitivity and autophagy of hypoxic human lung adenocarcinoma cell line A549

Background and purpose: Hypoxia induced the decreased radiosensitivity of tumor cells, which was the cause of tumor radioresistance and relapse and metastasis. During the course, HIF-1a played the most important role in the regulation of hypoxia. However, it’s still unknown about the effect of HIF-1...

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Autors principals: 邹燕梅, 熊华, 肖志平, 于世英, 袁响林
Format: Artigo
Idioma:Inglês
Publicat: Editorial Office of China Oncology 2013-01-01
Col·lecció:Zhongguo aizheng zazhi
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Accés en línia:http://www.china-oncology.com/thesisDetails#10.3969/j.issn.1007-3969.2013.06.003
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